Contrast-enhanced three-dimensional fusion sonography of small liver metastases with pathologic correlation
Purpose. To demonstrate that liver metastases with a diameter of ≤40 mm show characteristic features on three‐dimensional (3D) fusion sonographic images and that these sonographic findings can be correlated with histopathologic features of surgical specimens. Methods. Liver metastases measuring ≤40...
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Published in | Journal of clinical ultrasound Vol. 35; no. 1; pp. 1 - 8 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Hoboken
Wiley Subscription Services, Inc., A Wiley Company
01.01.2007
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Subjects | |
Online Access | Get full text |
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Summary: | Purpose.
To demonstrate that liver metastases with a diameter of ≤40 mm show characteristic features on three‐dimensional (3D) fusion sonographic images and that these sonographic findings can be correlated with histopathologic features of surgical specimens.
Methods.
Liver metastases measuring ≤40 mm were examined via contrast‐enhanced 3D fusion sonography. The characteristic sonographic findings of 17 tumor nodules in 11 patients with a histopathologically confirmed diagnosis of liver metastases were investigated, and their correspondence to the pathologic features were examined in 12 resected nodules.
Results.
On sonograms, central vessels were visualized in all 17 tumor nodules and peripheral vessels were visualized in 12 nodules. On histopathologic examination, the portal triad vessels corresponded to the central vessels and were located at the center of the tumors. A thin layer of peritumoral hepatocytes showing various changes was also observed, and a group of tiny vessels were seen running along this layer of cells.
Conclusions.
Liver metastases measuring 40 mm or less in diameter were characterized by the presence of both central and peripheral vessels on contrast‐enhanced 3D fusion sonography. There was good correlation between sonographic and histopathologic findings. © 2006 Wiley Periodicals, Inc. J Clin Ultrasound 2007 |
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Bibliography: | istex:10F766B7617373DCFB3CAE8F2DECD3F052AEBD17 ark:/67375/WNG-PPRXLPQ7-S ArticleID:JCU20299 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0091-2751 1097-0096 |
DOI: | 10.1002/jcu.20299 |