Efferent association pathways originating in the caudal prefrontal cortex in the macaque monkey

• Published in: Journal of comparative neurology (1911) Vol. 498; no. 2; pp. 227 - 251
• Main Authors: Petrides, M., Pandya, D.N.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 10.09.2006
• Subjects: Amino Acids - chemistry; Amino Acids - metabolism; Animals; association pathways; autoradiography; connections; Efferent Pathways - anatomy & histology; Efferent Pathways - metabolism; frontal cortex; Isotopes - chemistry; Isotopes - metabolism; Macaca - anatomy & histology; Macaca - metabolism; Magnetic Resonance Imaging; monkey; prefrontal cortex; Prefrontal Cortex - anatomy & histology; Prefrontal Cortex - metabolism
• ISSN: 0021-9967; 1096-9861
• DOI: 10.1002/cne.21048

The efferent association fibers from the caudal part of the prefrontal cortex to posterior cortical areas course via several pathways: the three components of the superior longitudinal fasciculus (SLF I, SLF II, and SLF III), the arcuate fasciculus (AF), the fronto‐occipital fasciculus (FOF), the cingulate fasciculus (CING F), and the extreme capsule (Extm C). Fibers from area 8Av course via FOF and SLF II, merging in the white matter of the inferior parietal lobule (IPL) and terminating in the caudal intraparietal sulcus (IPS). A group of these fibers turns ventrally to terminate in the caudal superior temporal sulcus (STS). Fibers from the rostral part of area 8Ad course via FOF and SLF II to the IPS and IPL and via the AF to the caudal superior temporal gyrus and STS. Some fibers from the rostral part of area 8Ad are conveyed to the medial parieto‐occipital region via FOF, to the STS via Extm C, and to the caudal cingulate gyrus via CING F. Fibers from area 8B travel via SLF I to the supplementary motor area and area 31 in the caudal dorsal cingulate region and via the CING F to cingulate areas 24 and 23 and the cingulate motor areas. Fibers from area 9/46d course via SLF I to the superior parietal lobule and medial parieto‐occipital region, via SLF II to the IPL. Fibers from area 9/46v travel via SLF III to the rostral IPL and the frontoparietal opercular region and via the CING F to the cingulate gyrus. J. Comp. Neurol. 498:227–251, 2006. © 2006 Wiley‐Liss, Inc.