Surface modification of titanium by anodic oxidation in phosphoric acid at low potentials. Part 2. In vitro and in vivo study

• Published in: Surface and interface analysis Vol. 45; no. 9; pp. 1395 - 1401
• Main Authors: Gomez Sanchez, A., Schreiner, W., Ballarre, J., Cisilino, A., Duffó, G., Ceré, S.
• Format: Journal Article
• Language: English
• Published: Chichester Blackwell Publishing Ltd 01.09.2013; Wiley; Wiley Subscription Services, Inc
• Subjects: Anodic; anodization; Anodizing; Biocompatibility; Bones; Condensed matter: electronic structure, electrical, magnetic, and optical properties; Condensed matter: structure, mechanical and thermal properties; Cross-disciplinary physics: materials science; rheology; Exact sciences and technology; in vivo implantation; Phosphoric acid; Physics; Reproduction; surface modification; Surgical implants; tests in SBF; Titanium; anodization; Anodizing; Transition elements; surface modification; Titanium; Surface treatments; tests in SBF; in vivo implantation
• ISSN: 0142-2421; 1096-9918
• DOI: 10.1002/sia.5298

Electrochemical studies in SBF solution were performed, in order to determine the best corrosion resistance condition, comparing as‐received titanium, covered with its native surface oxide, and titanium anodized in phosphoric acid. The results indicate that the anodic films obtained at a constant potential of 30 V have higher barrier effect, and the protective layer remains effective against the aggressive anions present in SBF after 30 days of immersion. Due to the promising corrosion performance in simulated biological media coupled with the biocompatible surface characteristics, anodic films on titanium obtained at 30 V were implanted on Wistar Rats to compare the osseointegration results of this modified surface with that corresponding to as‐received titanium. It was found that, after 8 weeks of implantation, although the amount of bone surrounding the implant did not differ across the two different surface implants conditions, bone formation at the implant interface was found to be more homogeneous in anodized titanium. Copyright © 2013 John Wiley & Sons, Ltd.