Novel and Efficient Method for Diagnosing Infective Endocarditis Using 16S Ribosomal RNA Gene Amplicon Sequence

We present 2 cases that both developed infective endocarditis and underwent mitral valve replacement. In addition to positive blood culture and echocardiographic findings, such as vegetation or mitral valve perforation, the 16S ribosomal RNA gene amplicon sequence approach used was helpful for disea...

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Published inJACC. Case reports Vol. 11; p. 101793
Main Authors Kataoka, Akihisa, Shiba, Takahiko, Katagiri, Sayaka, Koyama, Shuhei, Kito, Kento, Ota, Tatsuya, Katayama, Taiga, Ohsugi, Yujin, Nagai, Takahiko, Kobayashi, Ryota, Komatsu, Keiji, Urata, Masahiro, Imazuru, Tomohiro, Iwata, Takanori, Kozuma, Ken
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Inc 05.04.2023
Elsevier
Subjects
Case Report
echocardiography
endocarditis
genetics
mitral valve
genetics
MR
rRNA
echocardiography
mitral valve
MV
endocarditis
IE
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Summary:We present 2 cases that both developed infective endocarditis and underwent mitral valve replacement. In addition to positive blood culture and echocardiographic findings, such as vegetation or mitral valve perforation, the 16S ribosomal RNA gene amplicon sequence approach used was helpful for disease diagnosis. (Level of Difficulty: Intermediate.) [Display omitted]
ISSN:2666-0849
2666-0849
DOI:10.1016/j.jaccas.2023.101793