Evaluation of magnetic resonance imaging for bladder cancer detection following transurethral resection of bladder tumour (TURBT)

• Published in: Abdominal imaging Vol. 49; no. 7; pp. 2340 - 2348
• Main Authors: Khwaja, Samir A., Caglic, Iztok, Shaida, Nadeem, Colquhoun, Alexandra J., Turner, William, Barrett, Tristan
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.07.2024; Springer Nature B.V
• Subjects: Adult; Aged; Aged, 80 and over; Bladder; Bladder cancer; Cancer; Female; Gastroenterology; Hepatology; Humans; Imaging; Kidneys; Kidneys, Ureters, Bladder, Retroperitoneum; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Medical imaging; Medicine; Medicine & Public Health; Middle Aged; Performance evaluation; Predictive Value of Tests; Radiology; Retroperitoneum; Retrospective Studies; Sensitivity and Specificity; Transurethral Resection of Bladder; Tumors; Ureters; Urinary Bladder Neoplasms - diagnostic imaging; Urinary Bladder Neoplasms - pathology; Urinary Bladder Neoplasms - surgery; Magnetic resonance imaging; Staging; Bladder cancer; Transurethral resection of bladder tumour (TURBT); Diffusion weighted imaging (DWI)
• ISSN: 2366-0058; 2366-004X; 2366-0058
• DOI: 10.1007/s00261-024-04235-6

Purpose To evaluate the performance of MRI for detection of bladder cancer following transurethral resection of bladder tumour (TURBT). Methods This single-centre retrospective study included forty-one consecutive patients with bladder cancer who underwent bladder MRI after TURBT. Two uroradiologists retrospectively assessed the presence of tumour using bladder MRI with and without DWI (diffusion weighted imaging) using a five-point Likert scale. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated and inter-reader agreement was assessed. Histopathology was used as the reference standard. Results 24 out of 41 patients (58.5%) had no residual tumour or Tis (carcinoma in situ) after TURBT. Sensitivity, specificity, PPV and NPV for detection of tumour using T1WI (T1-weighted imaging) and T2WI (T2-weighted imaging) was 50.0%, 54.6%, 21.1%, and 81.8%, respectively and for T1WI, T2WI and DWI combined was 100%, 76.5%, 50.0% and 100%, respectively. Overestimation of tumour was more common than underestimation. MRI showed high accuracy for patients in whom there was no residual tumour (78.9%). Inter-reader agreement for tumour detection improved from fair (κ = 0.54) to moderate (κ = 0.70) when DWI was included. Conclusion Non-contrast MRI with DWI showed high sensitivity and relatively high specificity for detection of residual tumour after TURBT. Inter-reader agreement improved from fair to moderate with the addition of DWI. MRI can be useful after TURBT in order to guide further management. Graphical abstract