Organochlorine Pesticide Gradient Levels Among Maternal Adipose Tissue, Maternal Blood Serum and Umbilical Blood Serum

• Published in: Bulletin of environmental contamination and toxicology Vol. 86; no. 3; pp. 289 - 293
• Main Authors: Herrero-Mercado, Margarita, Waliszewski, S. M, Caba, M, Martínez-Valenzuela, C, Gómez Arroyo, S, Villalobos Pietrini, R, Cantú Martínez, P. C, Hernández-Chalate, F
• Format: Journal Article
• Language: English
• Published: New York New York : Springer-Verlag 01.03.2011; Springer-Verlag; Springer Nature B.V
• Subjects: Adipose tissue; Adipose Tissue - metabolism; Adult; Aquatic Pollution; Blood; Body fat; DDE; DDT - blood; DDT - metabolism; Dichlorodiphenyl Dichloroethylene - blood; Dichlorodiphenyl Dichloroethylene - metabolism; Earth and Environmental Science; Ecotoxicology; Environment; Environmental Chemistry; Environmental Health; Environmental Monitoring; Environmental Pollutants - blood; Environmental Pollutants - metabolism; Female; Fetal Blood - metabolism; Fetuses; Gas chromatography; Hexachlorocyclohexane; Human exposure; Humans; Hydrocarbons, Chlorinated - blood; Hydrocarbons, Chlorinated - metabolism; Lindane - blood; Lindane - metabolism; Maternal Exposure - statistics & numerical data; Nitrous oxide; Organic compounds; Organochlorine pesticides; Pesticides; Pesticides - blood; Pesticides - metabolism; Pollution; Pregnancy; Soil Science & Conservation; Toxicity; Waste Water Technology; Water Management; Water Pollution Control; Mexico; Blood; Adipose tissue; Organochlorine pesticides
• ISSN: 0007-4861; 1432-0800
• DOI: 10.1007/s00128-011-0204-4

The objective of the present study was to determine levels and calculate ratios of copartition coefficients among organochlorine pesticides β-HCH, pp′DDE, op′DDT and pp′DDT in maternal adipose tissue, maternal blood serum and umbilical blood serum of mother-infant pairs from Veracruz, Mexico. Organochlorine pesticides were analyzed in 70 binomials: maternal adipose tissue, maternal serum and umbilical cord serum samples, using gas chromatography with electron capture detection (GC-ECD). The results were expressed as mg/kg on fat basis. p,p′-DDE was the major organochlorine component, detected in every maternal adipose tissue (0.770 mg/kg), maternal serum sample (5.8 mg/kg on fat basis) and umbilical cord blood sample (6.9 mg/kg on fat basis). p,p′-DDT was detected at 0.101 mg/kg, 2.2 mg/kg and 5.9 mg/kg respectively, according to the order given above. β-HCH was detected at 0.027 mg/kg, 4.2 mg/kg and 28.0 mg/kg respectively. op′DDT was detected only in maternal adipose tissue at 0.011 mg/kg. The copartition coefficients among samples identify significant increases in concentrations from adipose tissue to maternal blood serum and to umbilical blood serum. The increase indicated that maternal adipose tissue released organochlorine pesticides to blood serum and that they are carried over to umbilical cord blood.