Core-Shell Structure of Gold Nanoparticles with Inositol Hexaphosphate Nanohybrids for Label-Free and Rapid Detection by SERS Nanotechnology

Gold nanoparticles bound with inositol hexaphosphate (IP6) (AuNPs/IP6) were prepared by in situ reduction of various concentrations of IP6 (0~320 µM) through modified Frens method for surface-enhanced Raman scattering (SERS) detection. The resultant AuNPs/IP6 were subject to characterization includi...

Full description

Saved in:
Bibliographic Details
Published inJournal of nanomaterials Vol. 2015; no. 2015; pp. 1 - 9
Main Authors Liu, Ting-Yu, Wang, Yuh-Lin, Wang, Kuan-Syun, Chan, Tzu-Yi, Yang, Ming-Chien, Liao, Hung-Liang, Huang, Li-Ying, Liu, Jin-Yuan, Mevold, Andreas H. H., Wang, Juen-Kai
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 01.01.2015
John Wiley & Sons, Inc
Subjects
Bacteria
Colleges & universities
Core-shell structure
Gold
Inositols
Light scattering
Morphology
Nanomaterials
Nanoparticles
Nanostructure
Nanotechnology
Raman scattering
Science
Sodium
X-ray photoelectron spectroscopy
Online AccessGet full text

Cover

More Information
Summary:Gold nanoparticles bound with inositol hexaphosphate (IP6) (AuNPs/IP6) were prepared by in situ reduction of various concentrations of IP6 (0~320 µM) through modified Frens method for surface-enhanced Raman scattering (SERS) detection. The resultant AuNPs/IP6 were subject to characterization including UV/Vis spectroscopy, transmission electron microscopy (TEM), dynamic light scattering (DLS), zeta potential, and X-ray photoelectron spectroscopy (XPS). The results showed that AuNPs with 65 µM of IP6 would result in a core AuNPs-shell (IP6 layer) structure, which exhibited the strongest SERS signal, due to the “hot spot effect” generated from the 1-2 nm interparticle gaps of AuNPs/IP6 nanohybrids (ionic interaction of IP6 and Au+). Furthermore, the reaction kinetics of Au and IP6 were also investigated in this work. Higher concentration of IP6 (190 and 260 µM) will make AuNPs become irregularly shaped, because IP6 is a basic salt and served as a pH mediator. The morphology and distribution of AuNPs were greatly improved by addition of 65 µM of IP6. This novel AuNPs/IP6 nanohybrid showed great stability and Raman enhancement. It is promising in the application of rapid and label-free biological detection of bacteria or tumor cells.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ISSN:1687-4110
1687-4129
DOI:10.1155/2015/857154