Ten new fawcettimine-related alkaloids from three species of Lycopodium

• Published in: Tetrahedron Vol. 67; no. 35; pp. 6561 - 6567
• Main Authors: Katakawa, Kazuaki, Mito, Hiroko, Kogure, Noriyuki, Kitajima, Mariko, Wongseripipatana, Sumphan, Arisawa, Munehisa, Takayama, Hiromitsu
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 02.09.2011; Elsevier
• Subjects: Alcaloids; Alkaloid; Alkaloids; Analytical, structural and metabolic biochemistry; Biological and medical sciences; Chemistry; Chemistry, Organic; Correlation; Derivatives; Fundamental and applied biological sciences. Psychology; General pharmacology; Heterocyclic compounds, pigments; Lycopodium; Medical sciences; Other biological molecules; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; Physical Sciences; Science & Technology; Spectroscopy; Structure elucidation; Tetrahedrons; Lycopodium; Structure elucidation; Alkaloid; ASYMMETRIC TOTAL SYNTHESES; CERNUANE-TYPE; Correlation; Hydroxylation; Molecular structure; Pharmacognosy; Pteridophyta; Medicinal plant; Plant origin; Isolation; Spectrophotometry; Structural analysis
• ISSN: 0040-4020; 1464-5416
• DOI: 10.1016/j.tet.2011.05.107

Ten new fawcettimine-related alkaloids, i.e., lycopoclavamines, lycoposquarrosamine-A, and other hydroxylated fawcettimine derivatives, were isolated from three species of Lycopodium ( Lycopodium clavatum, Lycopodium serratum, and Lycopodium squarrosum). The structures of the new alkaloids were elucidated by spectroscopic methods and chemical correlation. [Display omitted]