Detection of NDV-specific antibodies and the level of protection provided by a single vaccination in young chickens

Fourteen groups of young commercial chickens were immunized once with a live NDV vaccine using different vaccine doses and routes of vaccination in five experiments. Three to six weeks later, small groups were selected from each flock. Sera were tested by the haemagglutination-inhibition test and a...

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Bibliographic Details
Published inAvian pathology Vol. 27; no. 6; pp. 562 - 565
Main Authors Czifra, G., Mészáros, J., Horváth, E., Moving, V., Engström, B. E.
Format Journal Article
LanguageEnglish
Published England Taylor & Francis Group 01.12.1998
Taylor & Francis Ltd
Subjects
Birds
Ornithology
Pathology
Vaccines
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Summary:Fourteen groups of young commercial chickens were immunized once with a live NDV vaccine using different vaccine doses and routes of vaccination in five experiments. Three to six weeks later, small groups were selected from each flock. Sera were tested by the haemagglutination-inhibition test and a monoclonal antibody blocking ELISA, and the birds were challenged with a virulent NDV strain. Degree of protection was dose-dependent in those groups where the vaccine was administered orally at 3 weeks of age. Aerosol and eye drop vaccinations performed in day-old chicks provided full protection at 5 or 6 weeks of age. There was a good agreement between the two serological methods and positive results in any of the tests were reliable forecasts of protection.
Bibliography:ObjectType-Article-1
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ISSN:0307-9457
1465-3338
DOI:10.1080/03079459808419384