The acute and chronic toxicity of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) to the fathead minnow ( [formula omitted][formula omitted])

• Published in: Chemosphere (Oxford) Vol. 29; no. 3; pp. 567 - 579
• Main Authors: Burton, Dennis T., Turley, Steven D., Peters, Gregory T.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 1994; Elsevier
• Subjects: [formula omitted][formula omitted]; acute toxicity; Agnatha. Pisces; Animal, plant and microbial ecology; Applied ecology; Biological and medical sciences; chronic toxicity; Ecotoxicology, biological effects of pollution; Effects of pollution and side effects of pesticides on vertebrates; ELS; fathead minnow; Freshwater; Fundamental and applied biological sciences. Psychology; LOEC; munitions; NOEC; Pimephales promelas; RDX; fathead minnow; LOEC; acute toxicity; RDX; munitions; Pimephales promelas; NOEC; ELS; chronic toxicity; Nitro compound; Ecotoxicology; Nitrogen heterocycle; Toxicity; Acute; Industry; Freshwater environment; Vertebrata; Chronic; Six membered ring; Pisces; Concentration effect; Explosives; Water pollution; Armament
• ISSN: 0045-6535; 1879-1298
• DOI: 10.1016/0045-6535(94)90444-8

The acute 96-h LC50 for 15- to-17 day old fathead minnow ( Pimephales promelas ) exposed to hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) in aqueous solution was 12.7 mg/L at 25°C. A 28-day early life stage (ELS) test with the fathead minnow produced a lowest-observed-effect concentration (LOEC) and no-observed-effect concentration (NOEC) based on growth (both wet and dry weight) of 2.4 and 1.4 mg/L, respectively. A review of the literature shows that the chronic toxicity of RDX to fathead minnow is similar when evaluated in ELS, partial life cycle, and complete life cycle tests.