Antidiabetic property of fenugreek seed mucilage and spent turmeric in streptozotocin-induced diabetic rats

• Published in: Nutrition research (New York, N.Y.) Vol. 25; no. 11; pp. 1021 - 1028
• Main Authors: Kumar, G. Suresh, Shetty, A.K., Sambaiah, K., Salimath, P.V.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.11.2005; Elsevier Science
• Subjects: animal models; Biological and medical sciences; blood glucose; Curcuma longa; Diabetes; Fasting blood glucose; Feeding. Feeding behavior; fenugreek; Fenugreek seed mucilage; food processing wastes; Fundamental and applied biological sciences. Psychology; glucose tolerance; glycemic effect; mucilages; noninsulin-dependent diabetes mellitus; nutrient intake; nutritional intervention; Rat; rats; seed extracts; seeds; Spent turmeric; Trigonella foenum-graecum; turmeric; urine; Urine sugar; Vertebrates: anatomy and physiology, studies on body, several organs or systems; waste utilization; weight loss; Spent turmeric; Fasting blood glucose; Diabetes; Urine sugar; Rat; Fenugreek seed mucilage; Endocrinopathy; Urine; Seeds; Fasting; Diabetes mellitus; Rodentia; Glucose; Blood; Vertebrata; Mammalia; Animal; Fenugreek; Fast; Streptozotocin; Sugar
• ISSN: 0271-5317; 1879-0739
• DOI: 10.1016/j.nutres.2005.09.012

The beneficial effect of feeding fenugreek ( Trigonella foenum graecum) seed mucilage and spent turmeric ( Curcuma longa) on diabetic status was studied in streptozotocin-induced diabetic rats. Diabetic rats lost weight but body weights were improved by feeding spent turmeric than fenugreek seed mucilage. In diabetic rats, a 30% improvement in urine sugar and urine volume profiles was observed with feeding fenugreek seed mucilage and spent turmeric. Fasting blood glucose showed a 26% and 18% improvement with fenugreek seed mucilage and spent turmeric feeding to diabetic rats, respectively. Fenugreek seed mucilage compared with tumeric was more effective in ameliorating diabetic state.