Efficacy and tolerability of liposomal amphotericin B in Italian infants with visceral leishmaniasis

Visceral leishmaniasis (VL) due to Leishmania infantum is endemic in the Mediterranean area. Most children affected by the disease are between 1 and 3 years old. We report 2 Italian infants, both aged 8 months, with VL, whom we treated with liposomal amphotericin B (AmBisome registered ; Vestar, San...

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Published inTransactions of the Royal Society of Tropical Medicine and Hygiene Vol. 87; no. 4; p. 477
Main Authors di Martino, L., Raimondi, F., Scotti, S., Davidson, R.N., Gradoni, L., Giacchino, R.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.07.1993
Royal Society of Tropical Medicine and Hygiene
Subjects
Amphotericin B - administration & dosage
Amphotericin B - therapeutic use
Drug Carriers
Humans
Infant
Leishmania infantum
Leishmaniasis, Visceral - drug therapy
Liposomes
Italy
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Summary:Visceral leishmaniasis (VL) due to Leishmania infantum is endemic in the Mediterranean area. Most children affected by the disease are between 1 and 3 years old. We report 2 Italian infants, both aged 8 months, with VL, whom we treated with liposomal amphotericin B (AmBisome registered ; Vestar, San Dimas, California, USA).
Bibliography:ark:/67375/HXZ-H6L81QQW-D
istex:E3A42B46B37C79A59BA444270525E9CC3C12774F
Chemotherapy and chemoprophylaxis
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ISSN:0035-9203
1878-3503
DOI:10.1016/0035-9203(93)90045-R