Simple Allometric Diffusion-Based Biokinetic Model to Predict Cu(II) Uptake Across Gills of Freshwater Clam Corbicula fluminea

• Published in: Bulletin of environmental contamination and toxicology Vol. 84; no. 6; pp. 703 - 707
• Main Authors: Chen, W.-Y, Lin, C.-M, Ju, Y.-R, Liao, C.-M
• Format: Journal Article
• Language: English
• Published: New York New York : Springer-Verlag 01.06.2010; Springer-Verlag; Springer Nature B.V
• Subjects: Animals; Aquatic Pollution; Bioaccumulation; Biological magnification; Biouptake; Bivalvia; Copper; Copper - pharmacokinetics; Copper - toxicity; Corbicula - drug effects; Corbicula - growth & development; Corbicula - metabolism; Corbicula fluminea; Cu(II); Diffusion; Earth and Environmental Science; Ecotoxicology; Environment; Environmental Chemistry; Environmental Health; Estimating techniques; Fresh Water; Freshwater clam; Gills; Gills - growth & development; Gills - metabolism; Kinetics; Mass transfer; Models, Biological; Mollusks; Permeability; Pollution; Predictions; Soil Science & Conservation; Tissue Distribution; Toxicology; Waste Water Technology; Water Management; Water Pollutants, Chemical - pharmacokinetics; Water Pollutants, Chemical - toxicity; Water Pollution Control; Gills; Biouptake; Cu(II); Freshwater clam
• ISSN: 0007-4861; 1432-0800
• DOI: 10.1007/s00128-010-0011-3

The purpose of this study was to link Fick's type mass transfer and biokinetics together with Michaelis-Menten kinetics to arrive at a simple predictive framework for quantifying biouptake mechanisms in gills of freshwater clam Corbicula fluminea exposed to Cu(II). A diffusion-based Cu(II) influx and permeability can be calculated using physiological and allometric-related parameters. Simulations indicate that Cu(II) bioconcentration factor of gills was 42. Estimated steady-state Cu(II) gill uptake influx and permeability were 0.097 nmol cm⁻² s⁻¹ and 0.48 cm s⁻¹, respectively. The proposed simple allometric diffusion-based biokinetic model meets the need for describing nonequilibrium aspects of biouptake mechanisms in bivalve gills.