Lead, Cadmium, and Arsenic in Raw Milk Produced in the Vicinity of a Mini Mineral Concentrator in the Central Andes and Health Risk

• Published in: Biological trace element research Vol. 202; no. 5; pp. 2376 - 2390
• Main Authors: Chirinos-Peinado, Doris, Castro-Bedriñana, Jorge, Ríos-Ríos, Elva, Castro-Chirinos, Gianfranco, Quispe-Poma, Yubaly
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.05.2024; Springer Nature B.V
• Subjects: Absorption spectroscopy; Animals; Anthropogenic factors; Arsenic; Arsenic - analysis; Atomic absorption spectroscopy; Biochemistry; Biomedical and Life Sciences; Biotechnology; Cadmium; Cadmium - analysis; Concentrators; Consumption; Cow's milk; Dietary intake; Food Contamination - analysis; Health risk assessment; Health risks; Human influences; Humans; Lead; Lead - analysis; Life Sciences; Metals, Heavy - analysis; Milk; Milk - chemistry; Minerals - analysis; Nutrition; Oncology; Organophosphates; Pasture; Quotients; Risk Assessment; Spectral analysis; Spectrometry; Toxic substances; Hazard quotient; Lead; Cadmium; Dietary risk quotient; Arsenic; Bovine milk quality
• ISSN: 0163-4984; 1559-0720; 1559-0720
• DOI: 10.1007/s12011-023-03838-2

The bovine milk quality, safety, and security are of great concern mainly due to the dispersion of toxic substances from various anthropogenic activities and poor practices for organophosphates in agriculture use. This study evaluated the potential risk to human health from lead (Pb), cadmium (Cd), and arsenic (As) from the consumption of milk produced in an area of the Central Andes valley near a mini mineral concentrator by estimating the weekly intake (WI), dietary risk quotient (DRC), hazard quotient (THQ), and hazard index (HI) for the Peruvian population aged 2 to 85 years, in three scenarios of milk consumption by age (minimum, average, and maximum). Toxic element quantification was performed by flame atomic absorption spectrometry following standardized procedures. The mean amount ± standard deviation of Pb, Cd, and As in soils was 292±60.90, 3.54±1.58, and 5.60±2.20 mg/kg, the order of importance being Pb>As>Cd. The contents of Pb, Cd, and As in pastures were 23.17±10.02, 0.25±0.57, and 0.06±0.09 mg/kg, being from highest to lowest Pb>Cd>As. The means of Pb, Cd, and As content in 19 milk samples were 0.029±0.022, 0.007±0.006, and 0.010±0.004 mg/kg. Pb and Cd exceeded the maximum permissible limits (MPL), and the As was below the MPL. At all ages and milk consumption levels, the WI for Pb and Cd were below the estimated tolerable intake (TWI). The WI for As in < 19 years was higher than the TWI. The DRC for Pb and Cd at all three milk intake levels and all ages was < 1, and for As, it was > 1 in < 19 years, being the risk group. The TQH and HI for Pb and Cd were also > 1, signifying no health risk, and for As, the values were > 1 in < 11 years. Our results are valuable for preventing adverse health impacts from safe and innocuous milk consumption.