Surface structure of virions budding from L1210(V) gln − mouse leukemia cells

The surface structure of virions budding from L1210(V) gln − murine leukemia cells was studied by freeze-drying intact cells, and two types of virus particles were detected. One type possessed random 10-nm surface projections, similar to budding viruses on cells producing only murine leukemia virus...

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Published inVirology (New York, N.Y.) Vol. 75; no. 2; pp. 484 - 487
Main Authors Demsey, Anthony, Calvelli, Theresa A., Kawka, Douglas, Stackpole, Christopher W., Sarkar, Nurul H.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.01.1976
Subjects
Animals
Cell Line
Freeze Drying
Glycoproteins - analysis
Leukemia L1210 - microbiology
Leukemia Virus, Murine - analysis
Leukemia Virus, Murine - ultrastructure
Mammary Tumor Virus, Mouse - analysis
Mammary Tumor Virus, Mouse - ultrastructure
Viral Proteins - analysis
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Summary:The surface structure of virions budding from L1210(V) gln − murine leukemia cells was studied by freeze-drying intact cells, and two types of virus particles were detected. One type possessed random 10-nm surface projections, similar to budding viruses on cells producing only murine leukemia virus (MuLV). The other type possessed regularly arranged 5-nm projections, similar to budding viruses on cells producing only murine mammary tumor virus (MuMTV). Results of double antibody labeling are in agreement with the indication that individual viral envelopes on L1210(V) gln − cell viruses are homogeneous in their surface structure.
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ISSN:0042-6822
1096-0341
DOI:10.1016/0042-6822(76)90047-7