Bone Uptake of Vanadium in Mice: Simultaneous Tracing of V, Se, Sr, Y, Zr, Ru and Rh Using a Radioactive Multitracer

The radioactive multitracer technique, which enables simultaneous tracing of a number of elements in a variety of bio-systems and an accurate comparison of their biobehavior, was employed in a study on uptake behavior of trace elements in various mice tissues, focusing on uptake of V by bone. We fou...

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Published inJournal of trace elements in medicine and biology Vol. 10; no. 3; pp. 145 - 148
Main Authors Amano, R., Enomoto, S., Nobuta, M., Sakamoto, M., Tsujioka, R., Ambe, F.
Format Journal Article
LanguageEnglish
Published Germany Elsevier GmbH 1996
Subjects
Animals
Bone and Bones - metabolism
bone-seeking element
Male
Mice
Mice, Inbred Strains
radioactive multitracer technique
Radioisotopes
trace element
Trace Elements - pharmacokinetics
vanadium
Vanadium - pharmacokinetics
vanadium-48
trace element
vanadium-48
bone-seeking element
vanadium
radioactive multitracer technique
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Summary:The radioactive multitracer technique, which enables simultaneous tracing of a number of elements in a variety of bio-systems and an accurate comparison of their biobehavior, was employed in a study on uptake behavior of trace elements in various mice tissues, focusing on uptake of V by bone. We found that the bone uptake behavior of trace V closely resembles that of trace Sr and Y. It is suggested that V is a bone-seeking element which probably plays an important role in bone formation. The multitracer technique was thus shown to be useful for comparative studies of behavior of trace elements in living organisms.
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SourceType-Scholarly Journals-1
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ISSN:0946-672X
1878-3252
DOI:10.1016/S0946-672X(96)80024-1