Addition of MCP-1 and MIP-3β to the IL-8 appraisal in peritoneal fluid enhances the probability of identifying women with endometriosis

Highlights • Several chemokines have been tested for endometriosis so far. • For the first time the systematically selected chemokines were evaluated together in a multiplexed assay. • IL-8, MCP-1, and MIP-3β had statistically significant higher concentrations in the PF of women with endometriosis....

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Bibliographic Details
Published inJournal of reproductive immunology Vol. 109; pp. 66 - 73
Main Authors Borrelli, G.M, Kaufmann, A.M, Abrão, M.S, Mechsner, S
Format Journal Article
LanguageEnglish
Published Ireland Elsevier Ireland Ltd 01.06.2015
Subjects
Adult
Ascitic Fluid - metabolism
Biomarkers
Chemokine CCL19 - metabolism
Chemokine CCL2 - metabolism
Chemokines
Endometriosis
Endometriosis - metabolism
Female
Follicular Phase
Humans
Interleukin-8 - metabolism
Luteal Phase
Obstetrics and Gynecology
Panel of markers
Retrospective Studies
Biomarkers
Endometriosis
Panel of markers
Chemokines
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Summary:Highlights • Several chemokines have been tested for endometriosis so far. • For the first time the systematically selected chemokines were evaluated together in a multiplexed assay. • IL-8, MCP-1, and MIP-3β had statistically significant higher concentrations in the PF of women with endometriosis. • The combined assessment of MCP-1, MIP-3β, and IL-8 improved the likelihood of identifying patients with endometriosis.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:0165-0378
1872-7603
DOI:10.1016/j.jri.2015.01.003