Use of liquid chromatography–mass spectrometry in the analysis of residues of antibiotics in meat and milk

The advent of affordable LC–MS systems has led to a massive increase in the number of publications describing quantitative methods for the analysis and confirmation of veterinary drug residues. The lack of volatility and thermal instability of many antibiotics makes LC–MS the method of choice for th...

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Bibliographic Details
Published inJournal of Chromatography A Vol. 812; no. 1; pp. 77 - 98
Main Authors Kennedy, D.G, McCracken, R.J, Cannavan, A, Hewitt, S.A
Format Book Review Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 03.07.1998
Subjects
Animals
Anti-Bacterial Agents - analysis
Antibiotics
Chromatography, Liquid
Drug Residues - analysis
Mass Spectrometry
Meat - analysis
Milk - chemistry
Antibiotics
Reviews
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Summary:The advent of affordable LC–MS systems has led to a massive increase in the number of publications describing quantitative methods for the analysis and confirmation of veterinary drug residues. The lack of volatility and thermal instability of many antibiotics makes LC–MS the method of choice for their analysis. In this review, analytical methods for the determination of residues of each of the major classes of antibiotics are presented.
ISSN:0021-9673
DOI:10.1016/S0021-9673(98)00048-X