The special role of CXCL13 in Lyme neuroborreliosis: a case report

The diagnosis of chronic lyme neuroborreliosis can be a challenge even for experienced neurologists. The clinical picture may be multifaceted, including polyradiculitis to cranial nerve palsies, meningitis, encephalomyelitis, encephalopathy and peripheral neuropathy. We report on a patient presentin...

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Published inNeurological research and practice Vol. 4; no. 1; p. 3
Main Authors Erhart, Deborah K, Bracknies, Vera, Lutz-Schuhbauer, Susanne, Wigand, Sonja, Tumani, Hayrettin
Format Journal Article
LanguageEnglish
Published England Springer Nature B.V 17.01.2022
BioMed Central
BMC
Subjects
Borreliosis
Cerebrospinal fluid
Chemokines
Cranial nerves
CXCL13
CXCL13 protein
Encephalomyelitis
Encephalopathy
Letter to the Editor
Lyme disease
Lyme neuroborreliosis
Meningitis
Meningoencephalitis
Peripheral neuropathy
Polyradiculitis
Vascular diseases
Cerebrospinal fluid
Lyme neuroborreliosis
CXCL13
Meningoencephalitis
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Summary:The diagnosis of chronic lyme neuroborreliosis can be a challenge even for experienced neurologists. The clinical picture may be multifaceted, including polyradiculitis to cranial nerve palsies, meningitis, encephalomyelitis, encephalopathy and peripheral neuropathy. We report on a patient presenting with basal leptomeningoencephalitis associated with vasculopathy where the chemokine CXCL13 in cerebrospinal fluid played an important diagnostic role.
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ISSN:2524-3489
2524-3489
DOI:10.1186/s42466-022-00167-y