Biologically interfaced nanoplasmonic sensors
Understanding biointerfacial processes is crucial in various fields across fundamental and applied biology, but performing quantitative studies via conventional characterization techniques remains challenging due to instrumentation as well as analytical complexities and limitations. In order to acce...
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| Published in | Nanoscale advances Vol. 2; no. 8; pp. 313 - 3114 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
RSC
11.08.2020
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| Subjects | |
| Online Access | Get full text |
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| Summary: | Understanding biointerfacial processes is crucial in various fields across fundamental and applied biology, but performing quantitative studies
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conventional characterization techniques remains challenging due to instrumentation as well as analytical complexities and limitations. In order to accelerate translational research and address current challenges in healthcare and medicine, there is an outstanding need to develop surface-sensitive technologies with advanced measurement capabilities. Along this line, nanoplasmonic sensing has emerged as a powerful tool to quantitatively study biointerfacial processes owing to its high spatial resolution at the nanoscale. Consequently, the development of robust biological interfacing strategies becomes imperative to maximize its characterization potential. This review will highlight and discuss the critical role of biological interfacing within the context of constructing nanoplasmonic sensing platforms for biointerfacial science applications. Apart from paving the way for the development of highly surface-sensitive characterization tools that will spur fundamental biological interaction studies and improve the overall understanding of biological processes, the basic principles behind biointerfacing strategies presented in this review are also applicable to other fields that involve an interface between an inorganic material and a biological system.
This Minireview highlights and discusses the critical role of biological interfacing in constructing nanoplasmonic sensing platforms for biointerfacial science applications. |
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| Bibliography: | Nam-Joon Cho is MRS-Singapore Chair Professor in the School of Materials Science and Engineering at Nanyang Technological University. A recipient of the National Research Foundation Fellowship in Singapore, he received his PhD degree in Chemical Engineering from Stanford University, and completed a postdoctoral fellowship at the Stanford University School of Medicine. His research focuses on engineering artificial lipid membrane and tissue platforms to probe biological systems, and to develop enhanced therapeutic and drug delivery options that more effectively target infectious diseases, inflammatory disorders, and cancer. Bo Kyeong Yoon is a Research Fellow in the Translational Nanobioscience group within the School of Chemical Engineering at Sungkyunkwan University (SKKU). She received a joint PhD degree from Nanyang Technological University and the University of Natural Resources and Life Sciences (BOKU) in Austria, where she studied Materials Science and Engineering along with Food Chemistry and Biotechnology. Her research focuses on engineering strategies to inhibit membrane-enclosed pathogens, such as enveloped viruses, and related lipid membrane-based biosensor technologies. Abdul Rahim Ferhan is a Research Fellow in the Engineering in Translational Science Group at the Centre for Biomimetic Sensor Science of Nanyang Technological University (NTU). He received his B.Eng. degree in Chemical and Biomolecular Engineering and PhD degree in Biomedical Engineering from the School of Chemical and Biomedical Engineering, NTU. His research focuses on the development and application of novel nanoplasmonic sensing platforms for biomedical diagnostics and fundamental investigations into biomolecular interactions. Won-Yong Jeon is a Research Professor in the Translational Nanobioscience group within the School of Chemical Engineering at Sungkyunkwan University (SKKU). He received his B.S. and M.S. degrees in Chemistry and PhD degree in Nanobiomedical Science from Dankook University (DKU). His research focuses on the development and application of biosensing platforms for biomedical devices and electrochemical characterization of biomacromolecular interactions. ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| ISSN: | 2516-0230 2516-0230 |
| DOI: | 10.1039/d0na00279h |