Morphologic Variations in the Thyroid Glands of Cynomolgus Monkeys (macaca fascicularis)

Histologic and morphometric variations in the thyroid glands were investigated in twenty normal Cynomolgus monkeys. Heterogeneity in the pattern of colloid staining and the appearance of degenerating cells were frequently observed in the lumina of the thyroid follicles (45 and 50%, respectively). A...

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Bibliographic Details
Published inJournal of Toxicologic Pathology Vol. 13; no. 3; pp. 189 - 191
Main Authors Ishida, Katsuhiko, Narita, Kou, Ito, Kyoko, Izumisawa, Nobuyuki, Nii, Aisuke, Okamiya, Hideaki, Hanada, Takanori
Format Journal Article
LanguageEnglish
Published Tokyo JAPANESE SOCIETY OF TOXICOLOGIC PATHOLOGY 2000
The Japanese Society of Toxicologic Pathology
Japan Science and Technology Agency
Subjects
Cynomolgus monkey
Morphologic variation
Morphometry
Palpation thyroiditis
Thyroid gland
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Summary:Histologic and morphometric variations in the thyroid glands were investigated in twenty normal Cynomolgus monkeys. Heterogeneity in the pattern of colloid staining and the appearance of degenerating cells were frequently observed in the lumina of the thyroid follicles (45 and 50%, respectively). A few animals showed so-called ‘palpation thyroiditis’, characterized by numerous degenerating cells in the lumina of many follicles accompanied by multi-focal epithelial cell degeneration and interstitial inflammatory reactions. The size of the follicular lumina was different among animals and within an individual thyroid gland. Males usually had larger follicles than females.
ISSN:0914-9198
1881-915X
1347-7404
DOI:10.1293/tox.13.189