The diagnostic and prognostic value of red cell distribution width in cardiovascular disease; current status and prospective

The red blood cell distribution width (RDW) is an index of the heterogeneity of circulating red blood cell size, which along with other standard complete blood count (CBC) parameters are used to identify hematological system diseases. Besides hematological disorders, several clinical studies have sh...

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Published inBioFactors (Oxford) Vol. 45; no. 4; pp. 507 - 516
Main Authors Parizadeh, Seyed M., Jafarzadeh‐Esfehani, Reza, Bahreyni, Amirhossein, Ghandehari, Maryam, Shafiee, Mojtaba, Rahmani, Farzad, Parizadeh, Mohammar R., Seifi, Sima, Ghayour‐Mobarhan, Majid, Ferns, Gordon A., Avan, Amir, Hassanian, Seyed M.
Format Journal Article
LanguageEnglish
Published Hoboken, USA John Wiley & Sons, Inc 01.07.2019
Subjects
Acute Coronary Syndrome - blood
Acute Coronary Syndrome - diagnosis
Atrial Fibrillation - blood
Atrial Fibrillation - diagnosis
biomarker
Biomarkers - blood
Brain Ischemia - blood
Brain Ischemia - diagnosis
cardiovascular diseases
Erythrocyte Indices
Erythrocytes - pathology
Heart Failure - blood
Heart Failure - diagnosis
Humans
Peripheral Arterial Disease - blood
Peripheral Arterial Disease - diagnosis
Predictive Value of Tests
Prognosis
RDW
Stroke - blood
Stroke - diagnosis
RDW
biomarker
cardiovascular diseases
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Summary:The red blood cell distribution width (RDW) is an index of the heterogeneity of circulating red blood cell size, which along with other standard complete blood count (CBC) parameters are used to identify hematological system diseases. Besides hematological disorders, several clinical studies have shown that an increased in the RDW may be associated with other diseases including acute pancreatitis, chronic kidney disease, gastrointestinal disorders, cancer, and of special interest in this review, cardiovascular disease (CVD). The diagnostic and prognostic value of RDW in different CVD (acute coronary syndrome, ischemic cerebrovascular disease, peripheral artery disease, atrial fibrillation, heart failure, and acute ischemic stroke) has been reviewed in this article, to provide an understanding how its measurement may be applied to improve the management of these conditions.
Bibliography:Funding information
Mashhad University of Medical Sciences, Grant/Award Numbers: 950852, 951824
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0951-6433
1872-8081
DOI:10.1002/biof.1518