Salinomycin poisoning in point-of-lay turkeys [ionophore coccidiostat]

400 birds of a flock of 700 fed a diet containing salinomycin died over 7 days. No gross lesions were detected. Histological myopathy was most readily detected in leg muscles 5 to 7 days after ingestion. In feeding trials, individual susceptibility was found to vary greatly. A marked increase in pla...

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Bibliographic Details
Published inAustralian veterinary journal Vol. 66; no. 10; p. 326
Main Authors Griffiths, G.L, Hillier, P. (Western Australian Dept. of Agriculture, Perth. Animal Health Lab.), Sutherland, R.J. (Murdoch Univ., Murdoch (Australia). School of Veterinary Studies)
Format Journal Article
LanguageEnglish
Published England 01.10.1989
Subjects
Animal Feed - poisoning
Animals
Aspartate Aminotransferases - blood
Coccidiostats - poisoning
CONTAMINANTES
Creatine Kinase - blood
DINDON
ENVENENAMIENTO
Female
Food Contamination
INTOXICATION
Ionophores - poisoning
Muscles - pathology
PAVO
POLLUANT
Poultry Diseases - blood
Poultry Diseases - chemically induced
Poultry Diseases - enzymology
Poultry Diseases - pathology
Pyrans - poisoning
SALINOMICINA
SALINOMYCINE
Turkeys
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Summary:400 birds of a flock of 700 fed a diet containing salinomycin died over 7 days. No gross lesions were detected. Histological myopathy was most readily detected in leg muscles 5 to 7 days after ingestion. In feeding trials, individual susceptibility was found to vary greatly. A marked increase in plasma activities of creatine kinase and aspartate amino transferase preceded histological evidence of muscle necrosis.
Bibliography:L74
9000861
ISSN:0005-0423
1751-0813
DOI:10.1111/j.1751-0813.1989.tb09718.x