Increased MIBG activity in the uterine cervix due to menstruation

A 21-year-old woman with history of presacral ganglioneuroblastoma underwent I-MIBG scan for restaging. Planar images revealed increased MIBG activity in the upper pelvis, suggestive of disease recurrence. Complementary SPECT/CT images, however, localized the activity to the uterine cervix. Upon fur...

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Bibliographic Details
Published inClinical nuclear medicine Vol. 40; no. 2; p. 179
Main Authors Liu, Bin, Yang, Hua, Codreanu, Ion, Zhuang, Hongming
Format Journal Article
LanguageEnglish
Published United States 01.02.2015
Subjects
3-Iodobenzylguanidine
Cervix Uteri - diagnostic imaging
False Positive Reactions
Female
Ganglioneuroblastoma - diagnostic imaging
Humans
Menstruation
Multimodal Imaging
Radiopharmaceuticals
Tomography, Emission-Computed, Single-Photon
Tomography, X-Ray Computed
Young Adult
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Summary:A 21-year-old woman with history of presacral ganglioneuroblastoma underwent I-MIBG scan for restaging. Planar images revealed increased MIBG activity in the upper pelvis, suggestive of disease recurrence. Complementary SPECT/CT images, however, localized the activity to the uterine cervix. Upon further questioning, it has been established that the patient was menstruating. Subsequent follow-up scans proved normal, confirming the benign etiology of these findings. The case shows that radioactive blood accumulation in the uterine cervix can interfere with MIBG scan interpretation in menstruating patients.
ISSN:1536-0229
DOI:10.1097/RLU.0000000000000575