Heated Humidified High-Flow Nasal Cannula in Children: State of the Art

High-flow nasal cannula (HFNC) therapy is a non-invasive ventilatory support that has gained interest over the last ten years as a valid alternative to nasal continuous positive airway pressure (nCPAP) in children with respiratory failure. Its safety, availability, tolerability, and easy management...

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Published inBiomedicines Vol. 10; no. 10; p. 2353
Main Authors Venanzi, Annamaria, Di Filippo, Paola, Santagata, Chiara, Di Pillo, Sabrina, Chiarelli, Francesco, Attanasi, Marina
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 21.09.2022
MDPI
Subjects
Asthma
bronchiolitis
Children
Emergency medical care
Generators
Health aspects
heated humidified high-flow
Humidity
Intensive care
Intensive care units
Intubation
Length of stay
Meta-analysis
Nasal fossa
Oxygen therapy
Patients
Pediatric research
Pediatrics
respiratory failure
Review
Systematic review
Ventilators
United States
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Summary:High-flow nasal cannula (HFNC) therapy is a non-invasive ventilatory support that has gained interest over the last ten years as a valid alternative to nasal continuous positive airway pressure (nCPAP) in children with respiratory failure. Its safety, availability, tolerability, and easy management have resulted its increasing usage, even outside intensive care units. Despite its wide use in daily clinical practice, there is still a lack of guidelines to standardize the use of HFNC. The aim of this review is to summarize current knowledge about the mechanisms of action, safety, clinical effects, and tolerance of HFNC in children, and to propose a clinical practices algorithm for children with respiratory failure.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:2227-9059
2227-9059
DOI:10.3390/biomedicines10102353