Stability of cerebral blood flow and oxygen metabolism during normal aging

Cerebral blood flow and oxygen metabolism in aged normal subjects were measured with positron emission tomography and their relationship with brain atrophy was evaluated. Brain atrophy progressed in a linear fashion during aging while cerebral blood flow and oxygen metabolism were well preserved. Th...

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Published inGerontology (Basel) Vol. 36; no. 1; p. 43
Main Authors Itoh, M, Hatazawa, J, Miyazawa, H, Matsui, H, Meguro, K, Yanai, K, Kubota, K, Watanuki, S, Ido, T, Matsuzawa, T
Format Journal Article
LanguageEnglish
Published Switzerland 1990
Subjects
Aged
Aged, 80 and over
Aging - metabolism
Aging - physiology
Atrophy
Brain - diagnostic imaging
Brain - metabolism
Brain - pathology
Cerebrovascular Circulation
Female
Humans
Male
Middle Aged
Oxygen Consumption
Tomography, Emission-Computed
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Summary:Cerebral blood flow and oxygen metabolism in aged normal subjects were measured with positron emission tomography and their relationship with brain atrophy was evaluated. Brain atrophy progressed in a linear fashion during aging while cerebral blood flow and oxygen metabolism were well preserved. The finding suggests that brain atrophy is an aging process less dependent on cerebral blood flow and metabolism over the course of normal aging.
ISSN:0304-324X
DOI:10.1159/000213174