Xanthogranulomatous pyelonephritis in children: diagnostic and therapeutic aspects

Xanthogranulomatous pyelonephritis (XGP) is a rare, chronic inflammatory disease of the kidneys. It is characterized by destruction of renal parenchyma and accumulation of lipid-laden foamy macrophages. Diffuse and focal forms are known. The condition is mainly observed in middle-aged women, and it...

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Bibliographic Details
Published inJournal of medical ultrasonics (2001) Vol. 36; no. 1; pp. 33 - 37
Main Authors Eckoldt, Felicitas, Riebel, Thomas, Wolke, Stefan
Format Journal Article
LanguageEnglish
Published Japan Springer Japan 01.03.2009
Springer Nature B.V
Subjects
Case Report
Diagnostic systems
Imaging
Lipids
Macrophages
Medicine
Medicine & Public Health
Radiology
Ultrasound
magnetic resonance imaging
nephrectomy
color Doppler ultrasound
xanthogranulomatous pyelonephritis
outcome
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Summary:Xanthogranulomatous pyelonephritis (XGP) is a rare, chronic inflammatory disease of the kidneys. It is characterized by destruction of renal parenchyma and accumulation of lipid-laden foamy macrophages. Diffuse and focal forms are known. The condition is mainly observed in middle-aged women, and it is very rare in childhood. Of 32 nephrectomies carried out in children for various diseases in our hospital over the course of 2 years, there were two cases of diffuse XGP. In both cases, the preoperative diagnosis based on ultrasound findings was highly suggestive of XGP. We present the two cases and define the typical ultrasonographic signs for distinguishing XGP from other renal masses. The diagnostic and therapeutic management is discussed and an overview of the literature is given.
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ISSN:1346-4523
1613-2254
DOI:10.1007/s10396-008-0201-3