Validation of the French Version of the Colorectal-Specific Quality-of-life Questionnaires EORTC QLQ-CR38 and FACT-C

• Published in: Quality of life research Vol. 17; no. 3; pp. 437 - 445
• Main Authors: Rotonda, Christine, Conroy, T., Mercier, M., Bonnetain, F., Uwer, L., Miny, J., Montcuquet, P., Léonard, I., Adenis, A., Breysacher, G., Guillemin, F.
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer 01.04.2008; Springer Netherlands; Springer Nature B.V; Springer Verlag
• Subjects: Aged; Body image; Cancer; Cancer therapies; Chemotherapy; Colorectal cancer; Colorectal Neoplasms; Colorectal Neoplasms - drug therapy; Colorectal Neoplasms - psychology; Colorectal Neoplasms - surgery; Female; France; Health Surveys; Humans; Instrument Development and Evaluation; Life Sciences; Male; Medicine; Medicine & Public Health; Middle Aged; Prospective Studies; Psychological Tests; Psychometrics; Public Health; Quality of Life; Quality of Life - psychology; Quality of Life Research; Quantitative psychology; Questionnaires; Reproducibility of Results; Sexual dysfunction; Sociology; Surveys and Questionnaires; Symptoms; Weight loss; Wellbeing; France; Validation; FACT-C; EORTC QLQ-CR38; Colorectal cancer; Quality of life
• ISSN: 0962-9343; 1573-2649
• DOI: 10.1007/s11136-008-9322-9

Background The aim of this study was to test the psychometric properties of the French version of the European Organization for Research and Treatment (EORTC) quality-of-life colorectal questionnaire (QLQ-CR38) and the functional assessment of cancer therapy-colorectal version 4 (FACT-C). Method This prospective study included 209 patients with colorectal cancer: 71 undergoing chemotherapy, 56 radiation, 15 surgery, and 67 survivors. Patients first completed in random order the FACT-C and the EORTC QLQ-CR38 and were asked if they had any preference for either questionnaire. The timing of administration of instruments differed according to patients' treatment to better assess psychometric properties. Results The FACT-C showed good acceptability, good reproducibility and excellent internal consistency. The QLQ-CR38 had lower internal consistency. Patients did not express a preference for one survey over another. Conclusion This study confirms the value of the FACT-C and suggests some limits of the QLQ-CR38 for patients with colorectal cancer.