Clonal variation within a mucosal isolate derived from a patient with Leishmania (viannia) braziliensis infection

• Published in: Revista do Instituto de Medicina Tropical de São Paulo Vol. 33; no. 5; pp. 343 - 350
• Main Authors: CUBA-CUBA, C. A, EVANS, D, ROSA, A. DE C, MARSDEN, P. D
• Format: Journal Article
• Language: English
• Published: São Paulo Instituto de Medicina Tropical de São Paulo 01.09.1991; Instituto de Medicina Tropical
• Subjects: Animals; Antibodies, Monoclonal; Antigenic Variation; Biological and medical sciences; Biomarkers - analysis; Cricetinae; Electrophoresis, Cellulose Acetate; Fluorescent Antibody Technique; Human protozoal diseases; Humans; Infectious diseases; Isoenzymes - analysis; Leishmania braziliensis - enzymology; Leishmaniasis, Mucocutaneous - genetics; Leishmaniasis, Mucocutaneous - parasitology; Leshmaniasis; Medical sciences; Parasitic diseases; Protozoal diseases; TROPICAL MEDICINE; South America; Brazil; America; Infection; Protozoal disease; Vertebrata; Experimental disease; Mammalia; Animal; Rodentia; Phenotype variation; Mucocutaneous; Leishmaniasis; Hamster; Clone; Leishmania (Viannia) braziliensis; Clonal Variation; Serodemes; Zymodemes

Three isolates over 5 years from a patient with persistent relapsing mucosal leishmaniasis due to Leishmania (Viannia) braziliensis and 7 clones from one of these isolates were studied by zymodemes and serodemes analysis. Results showed evidences of clonal phenotypic variation. Eight isoenzymes mark...