Successful Treatment of Trichosporon beigelii Pneumonia with Itraconazole

• Published in: Clinical infectious diseases Vol. 26; no. 4; pp. 999 - 1000
• Main Authors: Canales, Miguel Angel, Sevilla, Julián, Gutierrez, Emilio Ojeda, Navarro, Fernando Hernández
• Format: Journal Article
• Language: English
• Published: Chicago, IL The University of Chicago Press 01.04.1998; University of Chicago Press
• Subjects: Adult; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antifungal agents; Antifungal Agents - therapeutic use; Azoles; Biological and medical sciences; Brief Reports; Female; Fever; Fungal infections; Humans; Infections; Itraconazole - therapeutic use; Medical sciences; Mycoses - diagnostic imaging; Mycoses - drug therapy; Pathogens; Pharmacology. Drug treatments; Pneumonia; Pneumonia - diagnostic imaging; Pneumonia - drug therapy; Pneumonia - microbiology; Sputum; Tomography, X-Ray Computed; triazoles; Trichosporon; Trichosporon beigelii; Human; Lung disease; Pneumonia; Mycosis; Respiratory disease; Treatment efficiency; Fungi; Infection; Case study; Antifungal agent; Chemotherapy; Treatment; Triazole derivatives; Female; Fungi Imperfecti; Thallophyta; Itraconazole; Trichosporon
• ISSN: 1058-4838; 1537-6591
• DOI: 10.1086/517648

Among patients with neoplastic diseases who are undergoing myeloablation, a growing number of uncommon fungal pathogens (including Trichosporon beigelii) have been reported to cause infection. Amphotericin B has limited activity against T. beigelii. On the basis of in vitro studies, some authors have suggested treatment with triazole compounds. We describe a patient with T. beigelii pneumonia whose condition responded to therapy with itraconazole.