Automated extraction of decision rules for leptin dynamics—A rough sets approach

• Published in: Journal of biomedical informatics Vol. 41; no. 4; pp. 667 - 674
• Main Authors: Brtka, Vladimir, Stokić, Edith, Srdić, Biljana
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2008
• Subjects: Adolescent; Adult; Algorithms; Artificial Intelligence; Biomarkers - blood; Decision Support Techniques; Diagnosis, Computer-Assisted - methods; Female; Humans; If–then rules; Indiscernibility; Leptin; Leptin - blood; Male; Middle Aged; Obesity - blood; Obesity - diagnosis; Pattern Recognition, Automated - methods; Rough sets theory; Rough sets theory; If–then rules; Indiscernibility; Leptin
• ISSN: 1532-0464; 1532-0480
• DOI: 10.1016/j.jbi.2008.01.005

A significant area in the field of medical informatics is concerned with the learning of medical models from low-level data. The goals of inducing models from data are twofold: analysis of the structure of the models so as to gain new insight into the unknown phenomena, and development of classifiers or outcome predictors for unseen cases. In this paper, we will employ approach based on the relation of indiscernibility and rough sets theory to study certain questions concerning the design of model based on if–then rules, from low-level data including 36 parameters, one of them leptin. To generate easy to read, interpret, and inspect model, we have used ROSETTA software system. The main goal of this work is to get new insight into phenomena of leptin levels while interplaying with other risk factors in obesity.