Subclinical hepatic fibrosis is associated with coronary microvascular dysfunction by myocardial perfusion reserve index: a retrospective cohort study

• Published in: The international journal of cardiovascular imaging Vol. 38; no. 7; pp. 1579 - 1586
• Main Authors: Kwan, Alan C., Wei, Janet, Lee, Brian P., Luong, Eric, Salto, Gerran, Nguyen, Trevor-Trung, Botting, Patrick G., Liu, Yunxian, Ouyang, David, Ebinger, Joseph E., Li, Debiao, Noureddin, Mazen, Thomson, Louise, Berman, Daniel S., Merz, C. Noel Bairey, Cheng, Susan
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.07.2022; Springer Nature B.V
• Subjects: Abnormalities; Blood platelets; Cardiac Imaging; Cardiology; Cardiovascular disease; Cardiovascular diseases; Cohort analysis; Coronary artery disease; Ejection fraction; Fibrosis; Health risks; Heart; Heart diseases; Imaging; Laboratories; Liver; Liver diseases; Magnetic resonance imaging; Medicine; Medicine & Public Health; Metabolism; Microvasculature; Original Paper; Patients; Perfusion; Phenotypes; Radiology; Risk analysis; Risk factors; Hepatic fibrosis; Coronary perfusion; Cardiac MRI

The heart–liver axis is of growing importance. Previous studies have identified independent association of liver dysfunction and fibrosis with adverse cardiac outcomes, but mechanistic pathways remain uncertain. We sought to understand the relations between the degree of hepatic fibrosis identified...