Plasma oxytocin levels in depression and their correlation with the temperament dimension of reward dependence

Evidence suggests that the neuropeptide oxytocin plays a role in social affiliation. This behaviour may be related more to personality dimensions than specific psychiatric diagnoses. This study investigated the relationship between plasma oxytocin levels and personality dimensions using the Temperam...

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Bibliographic Details
Published inJournal of psychopharmacology (Oxford) Vol. 20; no. 5; p. 656
Main Authors Bell, Caroline J, Nicholson, Helen, Mulder, Roger T, Luty, Sue E, Joyce, Peter R
Format Journal Article
LanguageEnglish
Published United States 01.09.2006
Subjects
Adolescent
Adult
Depressive Disorder - blood
Depressive Disorder - psychology
Female
Humans
Interpersonal Relations
Middle Aged
Oxytocin - blood
Personality - physiology
Psychiatric Status Rating Scales
Regression Analysis
Reward
Temperament - physiology
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Summary:Evidence suggests that the neuropeptide oxytocin plays a role in social affiliation. This behaviour may be related more to personality dimensions than specific psychiatric diagnoses. This study investigated the relationship between plasma oxytocin levels and personality dimensions using the Temperament and Character Inventory (TCI) in 60 outpatients with major depression. The strongest correlation was between plasma oxytocin levels and the temperament dimension of Reward Dependence (0.425 Pearson correlation). This suggested that 17% of the variance in plasma oxytocin levels was explained by the Reward Dependence scores. There was a significant positive correlation between plasma oxytocin levels and the Reward Dependence personality dimension.
ISSN:0269-8811
DOI:10.1177/0269881106060512