Frequency of fibromyalgia syndrome in breast cancer patients

• Published in: International journal of clinical oncology Vol. 18; no. 2; pp. 285 - 292
• Main Authors: Akkaya, Nuray, Atalay, Nilgün Simsir, Selcuk, Selin Taflan, Alkan, Hakan, Catalbas, Necdet, Sahin, Füsun
• Format: Journal Article
• Language: English
• Published: Japan Springer Japan 01.04.2013; Springer Nature B.V
• Subjects: Adult; Aged; Breast cancer; Breast Neoplasms - complications; Breast Neoplasms - epidemiology; Breast Neoplasms - pathology; Breast Neoplasms - surgery; Cancer Research; Chronic Pain - complications; Chronic Pain - epidemiology; Chronic Pain - pathology; Fatigue - complications; Fatigue - epidemiology; Fatigue - pathology; Female; Fibromyalgia; Fibromyalgia - complications; Fibromyalgia - epidemiology; Fibromyalgia - pathology; Humans; Medicine; Medicine & Public Health; Middle Aged; Oncology; Original Article; Quality of Life; Surgical Oncology; Surveys and Questionnaires; FM syndrome; Breast cancer; Chronic pain; Quality of life
• ISSN: 1341-9625; 1437-7772
• DOI: 10.1007/s10147-012-0377-9

Background We aimed to determine the frequency of fibromyalgia syndrome (FM) in operated breast cancer patients and to research the relationship between FM and the severity of fatigue and quality of life in these breast cancer patients. Methods The demographic data of 101 operated breast cancer patients were recorded. The patients who had pain were then classified as having regional pain (RP), widespread pain without FM (WP), and widespread pain with FM (WFM). The FM diagnosis was based on the American College of Rheumatology (ACR) criteria. The severity of fatigue was evaluated with the Brief Fatigue Inventory, the disease impact was evaluated with the Fibromyalgia Impact Questionnaire (FIQ), and the quality of life was evaluated with the European Organization for Research on Treatment of Cancer questionnaire Quality of Life-C30 (EORTC-QoL-C30). Results There was no pain in 38 (37.6%) patients, whereas there was pain in 63 (62.4%) patients ( N  = 42, 41.6% had RP, N  = 21, 20.8% had WP). Ten (9.9%) of the entire patient cohort were diagnosed as having FM according to the ACR criteria. There were no differences among the 3 groups in respect to demographic characteristics when patients were classified as RP ( N  = 42), WP ( N  = 11), and WFM ( N  = 10) groups. While there were negative correlations between the FIQ and EORTC-QoL-C30-function score ( r  = −0.727) and EORTC-QoL-C30-global score ( r  = −0.488), there was a positive correlation between the FIQ and EORTC-QoL-C30-symptom score ( r  = 0.726). Conclusion We note that the frequency of FM in the operated breast cancer patients in this study was higher than that reported in normal populations in the literature. Also, we found that the presence of FM had negative effects on the quality of life of the breast cancer patients. Accordingly, in the evaluation of widespread pain and complaints of fatigue in long-surviving breast cancer patients, after metastatic disease is excluded, the probability of FM should be kept in mind, so that appropriate treatment can be initiated to improve their functional status and quality of life.