Is Ginkgo biloba a cognitive enhancer in healthy individuals? A meta-analysis
Objective We conducted a meta‐analysis to examine whether Ginkgo biloba (G. biloba) enhances cognitive function in healthy individuals. Methods Scopus, Medline, Google Scholar databases and recent qualitative reviews were searched for studies examining the effects of G. biloba on cognitive function...
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Published in | Human psychopharmacology Vol. 27; no. 6; pp. 527 - 533 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
England
Blackwell Publishing Ltd
01.11.2012
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Subjects | |
Online Access | Get full text |
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Summary: | Objective
We conducted a meta‐analysis to examine whether Ginkgo biloba (G. biloba) enhances cognitive function in healthy individuals.
Methods
Scopus, Medline, Google Scholar databases and recent qualitative reviews were searched for studies examining the effects of G. biloba on cognitive function in healthy individuals. We identified randomised controlled trials containing data on memory (K = 13), executive function (K = 7) and attention (K = 8) from which effect sizes could be derived. The analyses provided measures of memory, executive function and attention in 1132, 534 and 910 participants, respectively.
Results
Effect sizes were non‐significant and close to zero for memory (d = −0.04: 95%CI −0.17 to 0.07), executive function (d = −0.05: 95%CI −0.17 to 0.05) and attention (d = −0.08: 95%CI −0.21 to 0.02). Meta‐regressions showed that effect sizes were not related to participant age, duration of the trial, daily dose, total dose or sample size.
Conclusions
We report that G. biloba had no ascertainable positive effects on a range of targeted cognitive functions in healthy individuals. Copyright © 2012 John Wiley & Sons, Ltd. |
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Bibliography: | istex:D8ED803CBE8B6A6DBC37690E0D162B3CAAB7FC62 ArticleID:HUP2259 ark:/67375/WNG-KKL98JNL-1 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 ObjectType-Review-3 content type line 23 |
ISSN: | 0885-6222 1099-1077 |
DOI: | 10.1002/hup.2259 |