Solid-phase combinatorial chemistry and novel tagging methods for identifying leads
Encoded combinatorial chemical synthesis on solid phase is a new paradigm in organic chemistry that provides chemists with powers similar to those enjoyed by molecular biologists. Encoded chemical libraries will have a profound impact on all endeavors that seek to identify molecules with optimized p...
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Published in | Current opinion in biotechnology Vol. 6; no. 6; pp. 632 - 639 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
England
Elsevier Ltd
1995
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Subjects | |
Online Access | Get full text |
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Summary: | Encoded combinatorial chemical synthesis on solid phase is a new paradigm in organic chemistry that provides chemists with powers similar to those enjoyed by molecular biologists. Encoded chemical libraries will have a profound impact on all endeavors that seek to identify molecules with optimized properties and to understand the factors governing molecular interactions. In particular, the discovery and optimization of new therapeutic and diagnostic drug molecules, traditionally a slow manual process, will be greatly accelerated by this technology. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Feature-3 ObjectType-Review-1 |
ISSN: | 0958-1669 1879-0429 |
DOI: | 10.1016/0958-1669(95)80104-9 |