Golden Hour Thrombolysis in Acute Ischemic Stroke: The Changing Pattern in South Korea

• Published in: Journal of stroke Vol. 23; no. 1; pp. 135 - 138
• Main Authors: Kim, Hyunsoo, Kim, Joon-Tae, Lee, Ji Sung, Kim, Beom Joon, Park, Jong-Moo, Kang, Kyusik, Lee, Soo Joo, Kim, Jae Guk, Cha, Jae-Kwan, Kim, Dae-Hyun, Park, Tai Hwan, Park, Sang-Soon, Lee, Kyung Bok, Lee, Jun, Hong, Keun-Sik, Cho, Yong-Jin, Park, Hong-Kyun, Lee, Byung-Chul, Yu, Kyung-Ho, Oh, Mi Sun, Kim, Dong-Eog, Ryu, Wi-Sun, Choi, Jay Chol, Kwon, Jee-Hyun, Kim, Wook-Joo, Shin, Dong-Ick, Sohn, Sung Il, Hong, Jeong-Ho, Park, Man-Seok, Choi, Kang-Ho, Cho, Ki-Hyun, Lee, Juneyoung, Bae, Hee-Joon
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Stroke Society 01.01.2021; 대한뇌졸중학회
• Subjects: Letter to the Editor; 신경과학
• ISSN: 2287-6391; 2287-6405
• DOI: 10.5853/jos.2020.04658

Intravenous tissue plasminogen activator (IV-tPA) is pivotal for the treatment of acute ischemic stroke; however, the benefit of IV-tPA treatment declines rapidly soon after stroke onset.1 These results support intensive efforts to reduce both onset-totreatment (OTT) time and door-to-treatment (DTT) time and serve as a basis for establishing an in-hospital and prehospital stroke care system. As these efforts require substantial expenditures of labor and capital, more real-world data are needed to assess the effect of golden hour thrombolysis for acute ischemic stroke. Moreover, understanding the current status and secular changes in IV-tPA treatment will be important to establish an appropriate stroke care system in the future. Therefore, we investigated the effect of golden hour thrombolysis and secular changes in time-to-treatment variables for IV-tPA for acute ischemic stroke by analyzing a prospective registry of 16 stroke centers in South Korea. KCI Citation Count: 0