The ages of the cancer-associated genes

• Published in: Seminars in oncology Vol. 46; no. 1; pp. 10 - 18
• Main Author: Stein, Wilfred D.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2019
• Subjects: Cosmic genes; Gene ages; Undrugged genes; Undrugged genes; Cosmic genes; Gene ages

In the accompanying manuscript (Litman and Stein, 2018) we list the ages of all the protein-coding genes and of many of the noncoding genes of the human genome. The present manuscript uses those results to derive the ages of the genes on the COSMIC list of somatic mutations in cancer. The lymphoma-a...