Characteristics of Myocardial Blood Vessels in Preterm Rats in the Late Postnatal Ontogeny

Immunohistochemical study (CD31 detection) and morphometric analysis (evaluation of specific volumes of cardiomyocytes and blood capillaries, diameter of blood capillaries, trophic index, and pericapillary diffusion zone) of the left ventricular myocardium in preterm (12 h and 24 h preterm) Wistar r...

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Published inBulletin of experimental biology and medicine Vol. 174; no. 3; pp. 391 - 394
Main Authors Ivanova, V. V., Zhigalina, A. S., Serebryakova, O. N., Sukhodolo, I. V., Milto, I. V.
Format Journal Article
LanguageEnglish
Published New York Springer US 2023
Springer
Springer Nature B.V
Subjects
Animals
Biomedical and Life Sciences
Biomedicine
Blood vessels
Capillaries
Cardiomyocytes
Cell Biology
Coronary Vessels
Heart
Heart diseases
Heart Ventricles
Immunohistochemistry
Infants (Premature)
Internal Medicine
Laboratory Medicine
Morphometry
Myocardium
Myocytes, Cardiac
Ontogeny
Pathology
Rats
Rats, Wistar
Vascular endothelial growth factor
Ventricle
preterm birth
myocardium
vascularization
vascular indices
experiment
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Summary:Immunohistochemical study (CD31 detection) and morphometric analysis (evaluation of specific volumes of cardiomyocytes and blood capillaries, diameter of blood capillaries, trophic index, and pericapillary diffusion zone) of the left ventricular myocardium in preterm (12 h and 24 h preterm) Wistar rats was carried out on postnatal days 56 and 180. A decrease in the trophic index and an increase in the zone of pericapillary diffusion in the myocardium of the left ventricle in preterm rats were shown, which indicates deterioration of the heart supply during the postnatal ontogeny.
Bibliography:ObjectType-Article-1
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ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-023-05714-4