Assessment of Lamellar Macular Hole and Macular Pseudohole With a Combination of En Face and Radial B-scan Optical Coherence Tomography Imaging

• Published in: American journal of ophthalmology Vol. 188; pp. 29 - 40
• Main Authors: Hirano, Masayuki, Morizane, Yuki, Kimura, Shuhei, Hosokawa, Mio, Shiode, Yusuke, Doi, Shinichiro, Toshima, Shinji, Takahashi, Kosuke, Hosogi, Mika, Fujiwara, Atsushi, Takasu, Ippei, Okanouchi, Toshio, Kawabata, Masaya, Shiraga, Fumio
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2018; Elsevier Limited
• Subjects: Aged; Aged, 80 and over; Classification; Diabetic retinopathy; Epiretinal Membrane - diagnostic imaging; Female; Fovea Centralis - diagnostic imaging; Humans; Macula Lutea - diagnostic imaging; Male; Medical imaging; Middle Aged; Morphology; Ophthalmology; Retina; Retinal Perforations - classification; Retinal Perforations - diagnostic imaging; Retinal Perforations - physiopathology; Retrospective Studies; Tomography, Optical Coherence - methods; Visual Acuity - physiology; Japan
• ISSN: 0002-9394; 1879-1891
• DOI: 10.1016/j.ajo.2018.01.016

To investigate lamellar macular hole (LMH) and macular pseudohole (MPH) using a combination of en face and radial B-scan OCT. Retrospective observational case series. Setting: Institutional study. Patient Population: En face and radial B-scan OCT images of 63 eyes of 60 patients diagnosed with LMH or MPH based on an international classification were reviewed. Observation Procedures: Cases were classified using en face images based on the presence/absence of epiretinal membrane (ERM), retinal folds, parafoveal epicenter of contractile ERM (PEC-ERM), and retinal cleavage. We compared the en face imaging–based classification system with the international classification system using radial B-scan images. We quantitatively evaluated visual function and macular morphology. Main Outcome Measures: Characterization of multimodal OCT-based subtypes of LMH and MPH. All cases showed ERM and were classified into 4 groups. In the first group, which lacked retinal folds and showed significantly lower visual acuity than the other groups, 81% of eyes had degenerative LMH. In the second group, which lacked PEC-ERM and retinal cleavage and showed significantly lower retinal fold depth, all eyes had MPH. The third group, in which 95% of eyes had symmetric tractional LMH, included eyes with retinal cleavage but without PEC-ERM, and this group showed higher circularity of the foveal aperture and cleavage area than the group with both these features, in which all eyes had asymmetric tractional LMH. Multimodal OCT enables classification of LMH and MPH based on pathologic conditions. Retinal traction in particular may be useful for determining treatment methods.