Intrathyroidal oncocytic parathyroid adenoma: A diagnostic pitfall on fine-needle aspiration

Oncocytic parathyroid adenoma is a rarely seen benign neoplasm of the parathyroid and intrathyroidal location of this lesion is also uncommon. It can be easily misdiagnosed as Hürthle cell thyroid neoplasm on fine‐needle aspiration (FNA). Here, an intrathyroidal oncocytic parathyroid adenoma in a 32...

Full description

Saved in:
Bibliographic Details
Published inDiagnostic cytopathology Vol. 38; no. 11; pp. 833 - 836
Main Authors Paker, Irem, Yilmazer, Demet, Yandakci, Kemal, Arikok, Ata Turker, Alper, Murat
Format Journal Article
LanguageEnglish
Published Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.11.2010
Subjects
Adenoma - metabolism
Adenoma - pathology
Adenoma, Oxyphilic - pathology
Adult
Biopsy, Fine-Needle
cytopathology
Diagnosis, Differential
Humans
Immunohistochemistry
Male
oncocytic
parathyroid adenoma
Parathyroid Neoplasms - metabolism
Parathyroid Neoplasms - pathology
Thyroid Neoplasms - pathology
Online AccessGet full text

Cover

More Information
Summary:Oncocytic parathyroid adenoma is a rarely seen benign neoplasm of the parathyroid and intrathyroidal location of this lesion is also uncommon. It can be easily misdiagnosed as Hürthle cell thyroid neoplasm on fine‐needle aspiration (FNA). Here, an intrathyroidal oncocytic parathyroid adenoma in a 32‐year‐old male is reported. Ultrasonography showed a nodule 2 cm in largest diameter in the left thyroid lobe. FNA revealed cellular smears containing monotonous oncocytic cells arranged in monolayered sheets, pseudopapillary structures and clusters within a rich vascular network. The case was reported as “suspicious for Hürthle cell thyroid neoplasm” on FNA. Frozen section examination showed intrathyroidal oncocytic parathyroid adenoma with a rim of normal parathyroid tissue. The diagnosis was also confirmed with immunohistochemical stains (TTF‐1, PTH, thyroglobulin) performed on permanent sections. Cytopathologic features of oncocytic parathyroid adenoma and Hürthle cell thyroid neoplasm are similar. It is important to keep oncocytic parathyroid adenoma in mind in the differential diagnosis of Hürthle cell thyroid neoplasm. Prior knowledge of clinical, radiological and laboratory data will avoid wrong cytopathologic diagnosis. Diagn. Cytopathol. 2010;38:833–836. © 2010 Wiley‐Liss, Inc.
Bibliography:istex:90E6BCDB8B3946E1A1E65608C0654E2409CD7319
ArticleID:DC21338
ark:/67375/WNG-SB9KNVKB-S
ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:8755-1039
1097-0339
DOI:10.1002/dc.21338