A multi-residue screening method for the determination of 73 pesticides and metabolites in fruit and vegetables using high-performance liquid chromatography/tandem mass spectrometry

• Published in: Rapid communications in mass spectrometry Vol. 18; no. 20; pp. 2443 - 2450
• Main Authors: Hetherton, Christel L., Sykes, Mark D., Fussell, Richard J., Goodall, David M.
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 30.10.2004
• Subjects: Chromatography, High Pressure Liquid - methods; Food Contamination - analysis; Fruit - chemistry; Fruit - metabolism; Pesticides - analysis; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Vegetables - chemistry; Vegetables - metabolism
• ISSN: 0951-4198; 1097-0231
• DOI: 10.1002/rcm.1645

A multi‐residue screening method was developed for the simultaneous analysis of 73 pesticides and their metabolites using high‐performance liquid chromatography coupled with electrospray tandem mass spectrometry. These pesticides were determined under a single set of experimental conditions involving a simple acetonitrile extraction without the requirement for a clean‐up step. Validation was achieved at 0.01 and 0.1 mg kg−1 levels in apple, lettuce and orange. Recoveries were in the range 77–124% for the majority of pesticides. © Crown Copyright 2004. Reproduced with the permission of Her Majesty's Stationery Office. Published by John Wiley & Sons, Ltd.