Quantitative analysis of cortical pyramidal neurons after corpus callosotomy

• Published in: Annals of neurology Vol. 54; no. 1; pp. 126 - 130
• Main Authors: Jacobs, Bob, Creswell, Johanna, Britt, Jonathan P., Ford, Kevin L., Bogen, Joseph E., Zaidel, Eran
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.07.2003; Willey-Liss
• Subjects: Adolescent; Adult; Biological and medical sciences; Cell Count; Corpus Callosum - surgery; Dendrites - ultrastructure; Epilepsy, Generalized - surgery; Frontal Lobe - ultrastructure; Humans; Male; Medical sciences; Neurons - ultrastructure; Neurosurgery; Neurosurgical Procedures - methods; Postoperative Period; Pyramidal Cells - ultrastructure; Skull, brain, vascular surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Human; Nervous system diseases; Epilepsy; Ablation; Corpus callosum; Cerebral disorder; Dendrite; Surgery; Central nervous system disease; Dendritic spine; Deafferentation; Pyramidal neuron; Quantitative analysis

This study quantitatively explored the dendritic/spine extent of supragranular pyramidal neurons across several cortical areas in two adult male subjects who had undergone a callosotomy several decades before death. In all cortical areas, there were numerous atypical, supragranular pyramidal neurons...