Hydroxyapatite for bone related applications derived from sea shell waste by simpleprecipitation method

The nano-hydroxyapatite (NHAp), NHAp/PEG and NHAp/PVP have been derived from Clam shell by precipitation method. The presence of characteristic FTIR peaks and XRD planes indicates the formation of NHAp. Surface morphology of NHAp, NHAp/PEG and NHAp/PVP appeared to be flake, majorly hexagonal and rod...

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Bibliographic Details
Published inJournal of Asian Ceramic Societies Vol. 8; no. 2; pp. 416 - 429
Main Authors Suresh Kumar, C., Dhanaraj, K., Vimalathithan, R.M., Ilaiyaraja, P., Suresh, G.
Format Journal Article
LanguageEnglish
Published Taylor & Francis 02.04.2020
Taylor & Francis Group
Subjects
Antibacterial activity
Hemolysis assay
Hydroxyapatite
Precipitation method
SBF analysis
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Summary:The nano-hydroxyapatite (NHAp), NHAp/PEG and NHAp/PVP have been derived from Clam shell by precipitation method. The presence of characteristic FTIR peaks and XRD planes indicates the formation of NHAp. Surface morphology of NHAp, NHAp/PEG and NHAp/PVP appeared to be flake, majorly hexagonal and rod clusters like structure, respectively. Sizes of the NHAp are in nanometer scale and size of NHAp/PVP is the lowest. The poor crystalline nature and high carbonate content presence in NHAp/PVP are assessed through crystallinity index, C/P ratio and CHNS analysis. EDX analysis shows the presence of HAp composition in NHAp. The calculated structural parameters expose that the NHAp/PVP shows favorable mechanical property. Good antibacterial activity is observed in NHAp/PVP against two bacteria strains. Hemolysis study also indicates that NHAp/PVP is non-hemolytic. Formation of complete apatite is found when NHAp/PVP immersed in SBF for 14 days. Thus, the NHAp/PVP derived from Clam shell may be useful for bone-related applications.
ISSN:2187-0764
2187-0764
DOI:10.1080/21870764.2020.1749373