Large bowel obstruction from advanced prostate cancer in a 41-year-old: the role of genetic testing

We report a rare presentation of an advanced prostate cancer (Gleason 10) in a 41-year-old man with complete large bowel obstruction relieved by loop colostomy. His young age prompted a search for a cause and genetic testing confirmed chromosome 10 PTEN deletion. His immediate family members were sc...

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Bibliographic Details
Published inSouth African journal of surgery Vol. 58; no. 3; p. 163
Main Authors Jonosky, J.B, de Villiers, N, Wadee, R, Chinegwundoh, F, Adam, A
Format Journal Article
LanguageEnglish
Published Pinelands South African Sports Medicine Association 01.09.2020
Medpharm Publications
Subjects
Gastrointestinal diseases
Genetic testing
Intestinal obstruction
Prostate cancer
South Africa
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Summary:We report a rare presentation of an advanced prostate cancer (Gleason 10) in a 41-year-old man with complete large bowel obstruction relieved by loop colostomy. His young age prompted a search for a cause and genetic testing confirmed chromosome 10 PTEN deletion. His immediate family members were screened and counselled appropriately. This case outlines the role of genetic testing in young males with prostate cancer.
ISSN:0038-2361
2078-5151
DOI:10.17159/2078-5151/2020/v58n3a3181