Preparation of chronic lung lymph fistulas in sheep

The majority of lung lymph in the sheep drains through a large caudal mediastinal lymph node. At a preliminary operation, we remove the systemic lymph contamination. We obtain lung lymph by cannulating the efferent duct of the node. We use a physiologic test in which we elevate systemic and pulmonar...

Full description

Saved in:
Bibliographic Details
Published inThe Journal of surgical research Vol. 19; no. 5; pp. 315 - 320
Main Authors Staub, Norman C., Bland, Richard D., Brigham, Kenneth L., Demling, Robert, Erdmann, A.John, Woolverton, William C.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.11.1975
Subjects
Animals
Female
Lung
Lymph
Sheep
Online AccessGet full text

Cover

More Information
Summary:The majority of lung lymph in the sheep drains through a large caudal mediastinal lymph node. At a preliminary operation, we remove the systemic lymph contamination. We obtain lung lymph by cannulating the efferent duct of the node. We use a physiologic test in which we elevate systemic and pulmonary venous pressures separately to show that the origin of the lymph is from the lung. The overall success rate in obtaining lung lymph flow for periods longer than 1 week is less than 50%. Successful animals are excellent models in which to study net lung fluid and protein flow.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0022-4804
1095-8673
DOI:10.1016/0022-4804(75)90056-6