Cohort Profile: French hospital database on HIV (FHDH-ANRS CO4)

• Published in: International journal of epidemiology Vol. 43; no. 5; pp. 1425 - 1436
• Main Authors: MARY-KRAUSE, Murielle, GRABAR, Sophie, DUVAL, Xavier, DUVIVIER, Claudine, LIEVRE, Laurence, ABGRALL, Sophie, BILLAUD, Eric, BOUE, François, BOYER, Laurence, CABIE, André, COTTE, Laurent, DE TRUCHIS, Pierre
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.10.2014; Oxford University Press (OUP)
• Subjects: Acquired Immunodeficiency Syndrome - complications; Acquired Immunodeficiency Syndrome - epidemiology; Adult; Antiretroviral Therapy, Highly Active; Biological and medical sciences; Cohort Studies; Coinfection; Databases, Factual - statistics & numerical data; Female; France - epidemiology; Hepatitis - complications; Hepatitis - epidemiology; Hepatitis B virus; HIV Infections - complications; HIV Infections - drug therapy; HIV Infections - epidemiology; Hospitals; Human immunodeficiency virus 1; Human immunodeficiency virus 2; Human viral diseases; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; Infectious diseases; Life Sciences; Male; Medical sciences; Middle Aged; Miscellaneous; Public health. Hygiene; Public health. Hygiene-occupational medicine; Risk Factors; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; France; ANE, France; Immunopathology; FHDH; Retroviridae; AIDS; cohort; Immune deficiency; Lentivirus; antiretroviral treatment; Infection; Virus; Concomitant disease; Chemotherapy; Treatment; French; HIV; comorbidities; Polypathology; Viral disease; Cohort study; Database; Hospital; Human immunodeficiency virus; Public health
• ISSN: 0300-5771; 1464-3685
• DOI: 10.1093/ije/dyu002

The French Hospital Database on HIV (FHDH) is a hospital-based multicentre open cohort with inclusions ongoing since 1989. The research objectives focus mainly on mid- and long-term clinical outcomes and therapeutic strategies, as well as severe AIDS and non-AIDS morbidities, and public health issues relative to HIV infection. FHDH also serves to describe HIV-infected patients receiving hospital care in France. FHDH includes data on more than 120,000 HIV-infected patients from 70 French general or university hospitals distributed throughout France. Patients are eligible for inclusion if they are infected by HIV-1 or HIV-2 and give their written informed consent. Standardized variables are collected at each outpatient visit or hospital admission during which a new clinical manifestation is diagnosed, a new treatment is prescribed or a change in biological markers is noted, and/or at least every 6 months. Since its inception, variables collected in FHDH include demographic characteristics, HIV-related biological markers, the date and type of AIDS and non AIDS-defining events, antiretroviral treatments and the date and causes of death, as reported in the medical records. Since 2005, data have also been collected on: co-infection with hepatitis B or C virus; alcohol and tobacco use; and non HIV-related biomarkers. Anyone can submit a research project by completing a standardized form available on the FHDH website (http://www.ccde.fr/_fold/fl-1385734776-429.pdf) or from the corresponding author, describing the context and objectives of the study. All projects are reviewed by the scientific committee.