The Ca/P range of nanoapatitic calcium phosphate cements

• Published in: Biomaterials Vol. 23; no. 19; pp. 4011 - 4017
• Main Authors: Driessens, F.C.M, Boltong, M.G, de Maeyer, E.A.P, Wenz, R, Nies, B, Planell, J.A
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.10.2002
• Subjects: Biocompatible Materials; Calcium - chemistry; Calcium deficient hydroxyapatite; Calcium phosphate cement; Calcium Phosphates - chemistry; Calcium potassium phosphate; Calcium potassium sodium phosphate; Dental Cements - chemistry; Durapatite - chemistry; Hydrogen-Ion Concentration; Ions; Magnesium - chemistry; Phosphates - chemistry; Potassium - metabolism; Potassium Compounds - chemistry; Potassium containing apatite; Sodium - metabolism; Time Factors; Calcium potassium sodium phosphate; Calcium phosphate cement; Potassium containing apatite; Calcium potassium phosphate; Calcium deficient hydroxyapatite
• ISSN: 0142-9612; 1878-5905
• DOI: 10.1016/S0142-9612(02)00151-5

Nanoapatites are apatites consisting of nanometer size crystals. The commercial calcium phosphate cements set by the precipitation of nanoapatitic calcium phosphates in the range 1.5⩽Ca/P<1.8. In this study it is shown that a continuum of nanoapatites can precipitate in the range 0.8<Ca/P⩽1.5. In order to be formed these nanoapatites need to incorporate K + ions. In addition they can incorporate some Na + ions. Upon immersion in aqueous solutions these nanoapatites loose phosphate, K + and Na + so that in an open system they are transformed into calcium deficient hydroxyapatite Ca 9(HPO 4)(PO 4) 5OH within about 2 months.