Risk Factors for Adverse Pregnancy Outcomes among Zhuang Ethnic Pregnant Women: A Cohort Study in Guangxi, China

• Published in: Current medical science Vol. 41; no. 2; pp. 219 - 227
• Main Authors: Feng, Bao-ying, Peng, Yang, Liang, Jun, Wu, Li, Jiang, Qun-jiao, Liu, Shun, Zeng, Xiao-yun, Huang, Dong-ping, Qiu, Xiao-qiang, Li, Han
• Format: Journal Article
• Language: English
• Published: Wuhan Huazhong University of Science and Technology 01.04.2021; Department of Sanitary Chemistry, School of Public Health, Guangxi Medical University, Nanning 530021, China%Department of Environmental and Occupational Health, School of Public Health, Guangxi Medical University, Nanning 530021, China%Department of Epidemiology and Health Statistics, School of Public Health, Guangxi Medical University, Nanning 530021,China
• Subjects: Adult; China - epidemiology; Cohort Studies; Ethnicity; Factor Analysis, Statistical; Female; Fetal Macrosomia - epidemiology; Fetus - pathology; Humans; Incidence; Infant, Low Birth Weight - physiology; Medicine; Medicine & Public Health; Pregnancy; Pregnancy Outcome - epidemiology; Premature Birth - epidemiology; Risk Factors; China; preterm birth; risk factors; cohort study; low birth weight; macrosomia; Zhuang ethnic
• ISSN: 2096-5230; 2523-899X; 1672-0733; 2523-899X; 1993-1352
• DOI: 10.1007/s11596-021-2339-9

Summary Risk factors for adverse pregnancy outcomes among Zhuang ethnic pregnant women are unclear. This study analyzed the incidence and risk factors related to preterm birth (PB), low birth weight (LBW) and macrosomia in Zhuang population. We conducted a prospective cohort study of 9965 Zhuang pregnancy women in Guangxi, China. Information on mothers and newborns was obtained by using questionnaires and referring to medical records. Multivariate logistic regression analyses were used to evaluate the association between related factors and adverse pregnancy outcomes. Our results showed that the incidence of PB, LBW and macrosomia in Zhuang people was 5.55%, 5.64% and 2.19%, respectively. Maternal age ≥36 years (OR=2.22, 95% CI: 1.51–3.27) was related to a higher incidence of PB. Those with pre-pregnancy body mass index (BMI) <18.5 kg/m 2 (OR=1.91, 95% CI: 1.45–2.51), and had a female fetus (OR=1.74, 95% CI: 1.36–2.23) were more likely to have LBW infants. Maternal age between 31 and 35 years (OR=1.76, 95% CI: 1.03–2.99) and pre-pregnancy overweight or obesity (OR=1.79, 95% CI: 1.15–2.80) were associated with a higher risk of macrosomia. The protective factors of macrosomia were maternal pre-pregnancy BMI <18.5 kg/m 2 (OR=0.30, 95% CI: 0.15–0.60) and female fetus (OR=0.41, 95% CI: 0.28–0.59). Our study provided a reference for maternal and childcare administration among Zhuang population.