Evaluation of the Calhoun Vision UV Light Adjustable Lens Implanted Following Cataract Removal

• Published in: Journal of refractive surgery (1995) Vol. 26; no. 10; pp. 716 - 721
• Main Authors: Hengerer, Fritz H, Conrad-Hengerer, Ina, Buchner, Sabine E, Dick, H. Burkhard
• Format: Journal Article
• Language: English
• Published: United States SLACK INCORPORATED 01.10.2010
• Subjects: Aged; Aged, 80 and over; Female; Humans; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Middle Aged; Phacoemulsification; Prognosis; Prospective Studies; Prosthesis Design; Refraction, Ocular - physiology; Ultraviolet Rays; Visual Acuity - physiology
• ISSN: 1081-597X; 1938-2391
• DOI: 10.3928/1081597X-20100408-02

Purpose: To evaluate the effectiveness of a silicone intraocular lens (IOL) that can be adjusted following implantation using ultraviolet (UV) irradiation. Methods: Prospective clinical trial of 40 patients (40 eyes) with visually significant cataract. Participants underwent small-incision phacoemulsification followed by implantation of a light-adjustable, silicone IOL (Light Adjustable Lens [LAL], Calhoun Vision). All patients were required to wear UV-protective eyewear at all times, until final lock-in. Pre- and postoperative clinical parameters included distance visual acuity and manifest refraction. Results: At average 2 weeks postoperative (range: 10 to 21 days), patients were seen and refracted to determine type and magnitude of refractive error needing correction. All patients required an initial adjustment of the LAL, whereas 28 required a second UV treatment and none required a third adjustment. At 4 months postoperative, mean refraction was 0.04±0.37 diopters (D) (range: −0.88 to 0.50 D), mean sphere was 0.24±0.40 D (range: −0.50 to 0.75 D), and mean cylinder was 0.41±0.25 D (range: 1.00 to 0.0 D). Eighty-one percent of eyes gained 2 or more lines of corrected distance visual acuity. Conclusions: The adjustment and lock-in procedures were well tolerated by patients. The Calhoun Vision LAL is a promising technology with the potential to eliminate postoperative refractive surprises of up to 2.00 D of refractive and cylindrical error following implantation.